A patented formula built to replenish the specific oils dry, cracked skin is missing — so skin can stay flexible and comfortable.
Dry, cracked skin is often low in the natural oils it needs to stay resilient, and ordinary creams aren't formulated to replace them. Here's what SkinIntegra B.I.O.™ (Bio-Identical Oils) does differently.
SkinIntegra started by profiling the lipid composition of healthy skin and identifying exactly what dry, compromised skin is missing. The result is five whole plant oils selected to match that profile — formulated to replenish the intercellular lipid matrix of the stratum corneum. Two form the patented core: Sacha Inchi — the highest plant-source of Omega-3 — and Sea Buckthorn, whose Omega-7 most closely mirrors skin's own lipids. Rice Bran, Sesame Seed, and Jojoba Seed complete the matrix. Together they replenish the lipid environment dry, cracked skin is missing — not only the oils, but the antioxidant and other protective components the barrier depends on.
Moisturizers reduce dryness temporarily. Urea creams soften callused skin. Both help — but neither replaces the natural oils the skin has lost. That's why cracks tend to come back. SkinIntegra B.I.O.™ is formulated to replenish the specific oils the skin has lost, matched to what healthy skin provides.
SkinIntegra B.I.O.™ is formulated to replenish the lipid environment the skin needs to feel and look its best. 25% urea and lactic acid work at the surface — hydrating and renewing the outer layers. Together, they address dryness and cracking from both directions, which is why patients who've relied on urea creams alone often notice a difference here.
Fragrance-free. Paraben-free. Alcohol-free. Petrolatum-free. Hypoallergenic. Free of salicylic acid. Formulated for daily use on the most sensitive, compromised skin.
Because SkinIntegra B.I.O.™ is matched to the skin's own lipid profile, the skin accepts it quickly — no greasy residue, no heavy texture. Most patients notice a difference within days. Calloused areas begin to soften, and surface cracks become less visible. In two weeks, skin looks and feels the way healthy skin should.
In a randomized, double-blind clinical trial at Western University of Health Sciences College of Podiatric Medicine, patients using SkinIntegra improved in dryness and cracking within 2 weeks, with no new or worsening irritation.
Study conducted by blinded podiatrist investigators. Results at 2-week and 4-week usage.
In the same randomized, double-blind trial, 48 adults with dry, cracked heels used either SkinIntegra (25% urea) or high-strength Urea-40 (40% urea). Both improved dryness and cracking comparably at 2 and 4 weeks. No SkinIntegra patient had new or worsening irritation; investigators separately noted irritation with extended Urea-40 use. Overall tolerability scores were comparable between groups.
APMA Seal of Approval · US Patent 10,786,441
Healthy skin produces sebum — a natural oil that seals the barrier by filling the spaces between skin cells. When skin is low in these essential lipids, the barrier loses its foundation, and cracks form that don't close on their own.
